The test looks for tiny traces of blood in the stool, a way of screening people for colon cancer. Fecal occult blood test: The fecal occult blood test (FOBT) is a lab test used to check stool samples for hidden (occult) blood. Importance AZ, CR, Methods The FIT-based CRC screening programme in the Veneto region (Italy) invited persons aged 50 to 69 . You can also reduce your risk of bowel cancer by: keeping physically active. Levi Free phone consultations with a registered nurse is available for people who test positive for a medical condition using one of LetsGetChecked tests. Further, she also stated that 9 out of 10 patients who have a positive FIT test DO NOT have cancer. But there is a small chance (about 3 out of 100) that colonoscopy misses cancer or a polyp that could later turn into cancer . This test uses antibodies that specifically react with a blood protein in the stool. et al. The Cologuard test has a 13% false-positive rate, which means 1 in 10 positive tests will incorrectly identify cancer or polyps. et al. Such a strategy is associated with higher cost, lower adherence, and higher risk for rare, but serious, complications.2-6. According to a 2014 clinical study, about 13% of results from Cologuard were false positives and 8% were false negatives. All studies assessed the accuracy of FIT for AN,26-37 but only 7 studies (4790 patients) reported data specifically for CRC.27,29,31-35 Prevalence of AN ranged between 3.2% and 14.5% and between 0.6% and 2.1% for CRC. Jiang Faecal immunochemical testing in bowel cancer screening: Estimating Can have false-positive test results. E, Nicols-Prez Several limitations have to be acknowledged about the evidence and the review itself. FIT has high overall diagnostic accuracy for CRC in increased-risk individuals. However, recommendations for increased-risk individuals are more aggressive and support only use of colonoscopy. Colonoscopy is currently the only recommended screening modality for participants at increased risk of CRC owing to personal or family history. Study supervision: Katsoula, Haidich, Tsapas, Giouleme.